Biostatistical Genetics And Genetic Epidemiology

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Biostatistical Genetics and Genetic Epidemiology

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Author by : Robert C. Elston
Languange Used : English, France, Spanish, Italia and chinese
Page : 831
Isbn : 9780471486312
Identifier : 0471486310
Release : 2002-04-22
Publisher by : John Wiley & Sons
Category : Mathematics
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Description : Read Now Biostatistical Genetics And Genetic Epidemiology by Robert C. Elston and you can download with pub, pdf, txt, doc, and more file format with free account. here′s a unique collection of 340 reproducible writing process activity sheets that capitalize on students′ natural interest in holidays and special events while reinforcing your writing skills curriculum! organized into ten monthly sections, september through june, each month including over 30 writing activity sheets like these for november: athletic words (sentence writing), last leaf on the tree (paragraph writing), and world without tv (essay writing).

Statistical Methods in Genetic Epidemiology

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Author by : Duncan C. Thomas
Languange Used : English, France, Spanish, Italia and chinese
Page : 464
Isbn : 9780199748051
Identifier : 0199748055
Release : 2004-01-29
Publisher by : Oxford University Press
Category : Medical
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Description : Read Now Statistical Methods In Genetic Epidemiology by Duncan C. Thomas and you can download with pub, pdf, txt, doc, and more file format with free account. this well-organized and clearly written text has a unique focus on methods of identifying the joint effects of genes and environment on disease patterns. it follows the natural sequence of research, taking readers through the study designs and statistical analysis techniques for determining whether a trait runs in families, testing hypotheses about whether a familial tendency is due to genetic or environmental factors or both, estimating the parameters of a genetic model, localizing and ultimately isolating the responsible genes, and finally characterizing their effects in the population. examples from the literature on the genetic epidemiology of breast and colorectal cancer, among other diseases, illustrate this process. although the book is oriented primarily towards graduate students in epidemiology, biostatistics and human genetics, it will also serve as a comprehensive reference work for researchers. introductory chapters on molecular biology, mendelian genetics, epidemiology, statistics, and population genetics will help make the book accessible to those coming from one of these fields without a background in the others. it strikes a good balance between epidemiologic study designs and statistical methods of data analysis.

A Statistical Approach to Genetic Epidemiology Concepts and Applications, with an e-Learning Platform

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Author by : Andreas Ziegler
Languange Used : English, France, Spanish, Italia and chinese
Page : 522
Isbn : 3527633669
Identifier : 9783527633661
Release : 2011-08-24
Publisher by : John Wiley & Sons
Category : Science
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Description : Read Now A Statistical Approach To Genetic Epidemiology by Andreas Ziegler and you can download with pub, pdf, txt, doc, and more file format with free account. this is the second edition of the successful textbook written by the prize-winning scientist andreas ziegler, former president of the german chapter of the international biometric society, and inke könig, who has been teaching the subject over many years. the book gives a comprehensive introduction into the relevant statistical methods in genetic epidemiology. the second edition is thoroughly revised, partly rewritten and includes now chapters on segregation analysis, twin studies and estimation of heritability. the book is ideally suited for advanced students in epidemiology, genetics, statistics, bioinformatics and biomathematics. like in the first edition the book contains many problems and solutions and it comes now optionally with an e-learning course created by friedrich pahlke. this e-learning course has been developed to complement the book. both provide a unique support tool for teaching the subject.

Basic Biostatistics for Geneticists and Epidemiologists A Practical Approach

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Author by : Robert C. Elston
Languange Used : English, France, Spanish, Italia and chinese
Page : 384
Isbn : 0470024917
Identifier : 9780470024911
Release : 2008-11-20
Publisher by : John Wiley & Sons
Category : Medical
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Description : Read Now Basic Biostatistics For Geneticists And Epidemiologists by Robert C. Elston and you can download with pub, pdf, txt, doc, and more file format with free account. anyone who attempts to read genetics or epidemiology research literature needs to understand the essentials of biostatistics. this book, a revised new edition of the successful essentials of biostatistics has been written to provide such an understanding to those who have little or no statistical background and who need to keep abreast of new findings in this fast moving field. unlike many other elementary books on biostatistics, the main focus of this book is to explain basic concepts needed to understand statistical procedures. this book: surveys basic statistical methods used in the genetics and epidemiology literature, including maximum likelihood and least squares. introduces methods, such as permutation testing and bootstrapping, that are becoming more widely used in both genetic and epidemiological research. is illustrated throughout with simple examples to clarify the statistical methodology. explains bayes’ theorem pictorially. features exercises, with answers to alternate questions, enabling use as a course text. written at an elementary mathematical level so that readers with high school mathematics will find the content accessible. graduate students studying genetic epidemiology, researchers and practitioners from genetics, epidemiology, biology, medical research and statistics will find this an invaluable introduction to statistics.

Analysis of Genetic Association Studies

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Author by : Gang Zheng
Languange Used : English, France, Spanish, Italia and chinese
Page : 414
Isbn : 1461422442
Identifier : 9781461422440
Release : 2012-01-10
Publisher by : Springer Science & Business Media
Category : Mathematics
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Description : Read Now Analysis Of Genetic Association Studies by Gang Zheng and you can download with pub, pdf, txt, doc, and more file format with free account. analysis of genetic association studies is both a graduate level textbook in statistical genetics and genetic epidemiology, and a reference book for the analysis of genetic association studies. students, researchers, and professionals will find the topics introduced in analysis of genetic association studies particularly relevant. the book is applicable to the study of statistics, biostatistics, genetics and genetic epidemiology. in addition to providing derivations, the book uses real examples and simulations to illustrate step-by-step applications. introductory chapters on probability and genetic epidemiology terminology provide the reader with necessary background knowledge. the organization of this work allows for both casual reference and close study.

Applied Statistical Genetics with R For Population-based Association Studies

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Author by : Andrea S. Foulkes
Languange Used : English, France, Spanish, Italia and chinese
Page : 252
Isbn : 038789554X
Identifier : 9780387895543
Release : 2009-04-28
Publisher by : Springer Science & Business Media
Category : Science
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Description : Read Now Applied Statistical Genetics With R by Andrea S. Foulkes and you can download with pub, pdf, txt, doc, and more file format with free account. statistical genetics has become a core course in many graduate programs in public health and medicine. this book presents fundamental concepts and principles in this emerging field at a level that is accessible to students and researchers with a first course in biostatistics. extensive examples are provided using publicly available data and the open source, statistical computing environment, r.

Fundamentals of Genetic Epidemiology

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Author by : Muin J. Khoury
Languange Used : English, France, Spanish, Italia and chinese
Page : 383
Isbn : 0195052889
Identifier : 9780195052886
Release : 1993
Publisher by : Oxford University Press, USA
Category : Medical
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Description : Read Now Fundamentals Of Genetic Epidemiology by Muin J. Khoury and you can download with pub, pdf, txt, doc, and more file format with free account. with continued progress in mapping and sequencing of the human genome, and increasing recognition of the role of genes in disease etiology, there is a need for a more sophisticated approach to the investigation of the causes of complex chronic diseases. this text integrates the principles, methods and approaches of epidemiology and genetics in the study of disease etiology. after a brief historical overview of genetics and epidemiology and their gradual rapprochement, the authors define the central theme of genetic epidemiology as the study of the role of genetic factors and their interaction with environmental factors in the occurrence of disease in populations. they describe fundamental research strategies of genetic epidemiology including population and family studies. among the former are the study of the distribution of genetic traits and the role of nonspecific genetic indicators (such as inbreeding and admixture) in the occurrence of diseases. among the latter are the analysis of familial aggregation of disease and its causes by epidemiologic methods as well as techniques of formal genetic analysis (variance components, segregation and linkage analysis). finally, the authors discuss the increasing applications of genetic epidemiology in preventive medicine, public health surveillance, and the emerging ethical issues regarding use of genetic information in society.

Biostatistics for Human Genetic Epidemiology

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Author by : Bertram K. C. Chan
Languange Used : English, France, Spanish, Italia and chinese
Page : 355
Isbn : 331993791X
Identifier : 9783319937915
Release : 2018-10-24
Publisher by : Springer
Category : Medical
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Description : Read Now Biostatistics For Human Genetic Epidemiology by Bertram K. C. Chan and you can download with pub, pdf, txt, doc, and more file format with free account. the book illustrates how biostatistics may numerically summarize human genetic epidemiology using r, and may be used successfully to solve problems in quantitative genetic epidemiology biostatistics for human genetic epidemiology provides statistical methodologies and r recipes for human genetic epidemiologic problems. it begins by introducing all the necessary probabilistic and statistical foundations, before moving on to topics related human genetic epidemiology, with r codes illustrations for various examples. this clear and concise book covers human genetic epidemiology, using r in data analysis, including multivariate data analysis. it examines probabilistic and statistical theories for modeling human genetic epidemiology – leading the readers through an effective epidemiologic model, from simple to advanced levels. classical mathematical, probabilistic, and statistical theory are thoroughly discussed and presented. this book also presents r as a calculator and using r in data analysis. additionally, it covers advanced human genetic data concepts, the study of human genetic variation, manhattan plots, as well as the procedures for multiple comparison. numerous worked examples are provided for illustrations of concepts and real-life applications. biostatistics for human genetic epidemiology is an ideal reference for professionals and students in medicine (particularly in preventive medicine and public health medical practices), as well as in genetics, epidemiology, and biostatistics.

The Fundamentals of Modern Statistical Genetics

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Author by : Nan M. Laird
Languange Used : English, France, Spanish, Italia and chinese
Page : 226
Isbn : 9781441973382
Identifier : 1441973389
Release : 2010-12-13
Publisher by : Springer Science & Business Media
Category : Medical
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Description : Read Now The Fundamentals Of Modern Statistical Genetics by Nan M. Laird and you can download with pub, pdf, txt, doc, and more file format with free account. this book covers the statistical models and methods that are used to understand human genetics, following the historical and recent developments of human genetics. starting with mendel’s first experiments to genome-wide association studies, the book describes how genetic information can be incorporated into statistical models to discover disease genes. all commonly used approaches in statistical genetics (e.g. aggregation analysis, segregation, linkage analysis, etc), are used, but the focus of the book is modern approaches to association analysis. numerous examples illustrate key points throughout the text, both of mendelian and complex genetic disorders. the intended audience is statisticians, biostatisticians, epidemiologists and quantitatively- oriented geneticists and health scientists wanting to learn about statistical methods for genetic analysis, whether to better analyze genetic data, or to pursue research in methodology. a background in intermediate level statistical methods is required. the authors include few mathematical derivations, and the exercises provide problems for students with a broad range of skill levels. no background in genetics is assumed.

Human Genome Epidemiology A Scientific Foundation for Using Genetic Information to Improve Health and Prevent Disease

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Author by : Muin J. Khoury
Languange Used : English, France, Spanish, Italia and chinese
Page : 549
Isbn : 0195146743
Identifier : 9780195146745
Release : 2004
Publisher by : Oxford University Press
Category : Medical
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Description : Read Now Human Genome Epidemiology by Muin J. Khoury and you can download with pub, pdf, txt, doc, and more file format with free account. advances in genomics are expected to play a central role in medicine and public health in the future by providing a genetic basis for disease prediction and prevention. the transplantation of human gene discoveries into meaningful actions to improve health and prevent disease depends on scientific information from multiple disciplines, including epidemiology. this book describes the important role that epidemiologic methods play in the continuum from gene discovery to the development and application of genetic tests. it proceeds systematically from the fundamentals of genome technology and gene discovery, to epidemiologic approaches to gene characterization in the population, to the evaluation of genetic tests and their use in health services. these methodologic approaches are then illustrated with several disease-specific case studies. the book provides a scientific foundation that will help researchers, policy makers, and practitioners integrate genomics into medical and public health practice.

Genetic Epidemiology

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Author by : M. Dawn Teare
Languange Used : English, France, Spanish, Italia and chinese
Page : 242
Isbn : 9781603274159
Identifier : 1603274154
Release : 2010-12-20
Publisher by : Humana Press
Category : Medical
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Description : Read Now Genetic Epidemiology by M. Dawn Teare and you can download with pub, pdf, txt, doc, and more file format with free account. arising from firm foundations laid by mathematical population genetics, clinical genetics, and statistical epidemiology, genetic epidemiology attempts to identify the many components of risk attributable to genes, environments, and interactions, and the course of its research can follow many diverse paths. in genetic epidemiology, the success of genome-wide association studies in their identification of hundreds of disease susceptibility loci has inspired renowned experts to contribute thorough methodologies, which aim to bring together bioinformaticians, geneticists, clinicians, statisticians, and epidemiologists in the study of this vital field. the volume opens with chapters covering the basics; however, it quickly moves on to coverage of more specialist topics such as twin studies, mendelian randomization, genetic association studies, more advanced areas, as well as case studies. as a part of the highly successful methods in molecular biologytm series, this work provides the detailed description of the application and analysis of the most commonly employed methods that are necessary for a firm grounding in the field. authoritative and cutting-edge, genetic epidemiology aims to provide a basic framework for crucial interdisciplinary communication and understanding suited to newcomers to the field as well as experienced researchers and graduate level students.

Handbook of Statistical Genetics

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Author by : David J. Balding
Languange Used : English, France, Spanish, Italia and chinese
Page : 1616
Isbn : 9780470997628
Identifier : 0470997621
Release : 2008-06-10
Publisher by : John Wiley & Sons
Category : Science
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Description : Read Now Handbook Of Statistical Genetics by David J. Balding and you can download with pub, pdf, txt, doc, and more file format with free account. the handbook for statistical genetics is widely regarded as the reference work in the field. however, the field has developed considerably over the past three years. in particular the modeling of genetic networks has advanced considerably via the evolution of microarray analysis. as a consequence the 3rd edition of the handbook contains a much expanded section on network modeling, including 5 new chapters covering metabolic networks, graphical modeling and inference and simulation of pedigrees and genealogies. other chapters new to the 3rd edition include human population genetics, genome-wide association studies, family-based association studies, pharmacogenetics, epigenetics, ethic and insurance. as with the second edition, the handbook includes a glossary of terms, acronyms and abbreviations, and features extensive cross-referencing between the chapters, tying the different areas together. with heavy use of up-to-date examples, real-life case studies and references to web-based resources, this continues to be must-have reference in a vital area of research. edited by the leading international authorities in the field. david balding - department of epidemiology & public health, imperial college an advisor for our probability & statistics series, professor balding is also a previous wiley author, having written weight-of-evidence for forensic dna profiles, as well as having edited the two previous editions of hsg. with over 20 years teaching experience, he’s also had dozens of articles published in numerous international journals. martin bishop – head of the bioinformatics division at the hgmp resource centre as well as the first two editions of hsg, dr bishop has edited a number of introductory books on the application of informatics to molecular biology and genetics. he is the associate editor of the journal bioinformatics and managing editor of briefings in bioinformatics. chris cannings – division of genomic medicine, university of sheffield with over 40 years teaching in the area, professor cannings has published over 100 papers and is on the editorial board of many related journals. co-editor of the two previous editions of hsg, he also authored a book on this topic.