Cardiac Glycosides Part I

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Cardiac Glycosides Part II: Pharmacokinetics and Clinical Pharmacology

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Author by : no defined
Languange Used : English, France, Spanish, Italia and chinese
Page : 394
Isbn : 3642681662
Identifier : 9783642681660
Release : 2012-12-06
Publisher by : Springer Science & Business Media
Category : Medical
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Description : Read Now Cardiac Glycosides by no defined and you can download with pub, pdf, txt, doc, and more file format with free account. the pharmacokinetics of digitalis glycosides have been the subject of extensive re view (iisalo, 1977; aronson, 1980; perrier et ai., 1977). research on glycoside kinetics has progressed at a rapid pace, requiring continuing reevaluation of the state of our understanding of this problem. the present article focuses on the effect of disease states (renal, gastrointestinal, thyroid, and cardiac) on the absorption, distribution, and clearance of a number of digitalis glycosides. evidence is critically reviewed, and interpreted with respect to possible clinical implications. a. renal insufficiency i. strophanthin strophanthin disposition in renal failure has been evaluated in only two studies. kramer et ai. (1970) determined an elimination half-life of 14 h in normals as com pared to 60 h in anuric patients. similar results were reported by brass and pm lipps (1970) using tritiated strophanthin. they found a half-life value of 18 h in healthy individuals as compared to 68 h in anuric patients. the findings clearly in dicate that the elimination half-life of strophanthin is prolonged in renal failure.

Cardiac Glycosides Part I: Experimental Pharmacology

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Author by : Kurt Greeff
Languange Used : English, France, Spanish, Italia and chinese
Page : 682
Isbn : 9783540109174
Identifier : 354010917X
Release : 1981-09-01
Publisher by : Springer
Category : Medical
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Description : Read Now Cardiac Glycosides by Kurt Greeff and you can download with pub, pdf, txt, doc, and more file format with free account. following the monographs by straub (1924) and lendle (1935), this is the third contribution to the "pharmacology of cardiac glycosides" within the handbook of experimental pharmacology, which was founded by arthur heffter and con tinued by wolfgang heubner. because of the need created by the length of time that had elapsed since lendle's work, the editorial board requested the rapid ap pearance of this 56th volume, which represents current knowledge of the pharma cology and clinical pharmacology of cardiac glycosides. in order to avoid any delay, numerous authors were invited to contribute because shorter contributions take less time to prepare and are consequently more up-to-date. the disadvantage is that some overlap between certain chapters could not be avoided, despite the editor's efforts. overlapping can, however, actually be useful, in that differing opinions may be provided and topical issues discussed from varying viewpoints. this re minds the reader that scientific horizons in medicine should often be widened or revised. i would like to thank dr. alanna fox and dr. k. anantharaman for their help and advice in the revision of certain chapters. i am also grateful to springer verlag, and particularly to mr. winstanley and mr. emerson, for their contribu tion to the completion of this volume through translation and corrections. in con clusion i would like to thank mrs. walker, mr. bischoff, mrs. seeker, and mr. bergstedt of springer-verlag for their helpful support.

Cardiac Glycosides 1785–1985 Biochemistry — Pharmacology — Clinical Relevance

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Author by : E. Erdmann
Languange Used : English, France, Spanish, Italia and chinese
Page : 552
Isbn : 3662112922
Identifier : 9783662112922
Release : 2013-06-29
Publisher by : Springer Science & Business Media
Category : Medical
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Description : Read Now Cardiac Glycosides 1785 1985 by E. Erdmann and you can download with pub, pdf, txt, doc, and more file format with free account. the bicentenary of william withering's now famous medical report entitled "an account of the foxglove and some of its medical uses" has given us the occasion to analyze the state of the art. cardiac glycosides in 1985 are considered tobe the basis for medical treatment of myocardial failure, together with diuretics and vasodilators in the more severe cases. nevertheless, the controversy as to their exact place in the treatment of heart failure with sinus rhythm has never ceased. although cardiac glycosides are of unquestionable value in tachycardia caused by atrial fibrillation or atrial flutter, the chronic use of these drugs in sinus rhythm is not generally accepted. the development of tolerance has been reported. it is of interest that withering hirnself wrote: "-let it (foxglove) be continued until it either acts on the kidneys, the stomach, the pulse, or the bowels; iet it be stopped upon the first appearance of any of these effects, and i will maintain that the patient will not suffer from its exhibition, nor the practitioner be disappointed in any reasonable expectation. " in west germany alone, more than three million patients (about 5% of the total population) are constantly taking cardiac glycosides. these drugs are the most prescribed medicaments in many countries. thus, we considered it worthwhile and necessary to review in a critical way today's knowledge about the foxglove; to report new findings and to evaluate old statements.

Cardiac Glycosides: Pharmacokinetics and Clinical Pharmacology

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Author by : K. Greeff
Languange Used : English, France, Spanish, Italia and chinese
Page : 394
Isbn :
Identifier : OCLC:38012479
Release : 1981
Publisher by : no defined
Category :
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An Account of the Foxglove, and Some of Its Medical Uses With Practical Remarks on Dropsy and Other Diseases

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Author by : William Withering
Languange Used : English, France, Spanish, Italia and chinese
Page : 207
Isbn :
Identifier : UOM:39015029859629
Release : 1785
Publisher by : no defined
Category : Digitalis
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Cardiac Glycosides 1785–1985 Biochemistry — Pharmacology — Clinical Relevance

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Author by : E. Erdmann
Languange Used : English, France, Spanish, Italia and chinese
Page : 552
Isbn : 3662112922
Identifier : 9783662112922
Release : 2013-06-29
Publisher by : Springer Science & Business Media
Category : Medical
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Description : Read Now Cardiac Glycosides 1785 1985 by E. Erdmann and you can download with pub, pdf, txt, doc, and more file format with free account. the bicentenary of william withering's now famous medical report entitled "an account of the foxglove and some of its medical uses" has given us the occasion to analyze the state of the art. cardiac glycosides in 1985 are considered tobe the basis for medical treatment of myocardial failure, together with diuretics and vasodilators in the more severe cases. nevertheless, the controversy as to their exact place in the treatment of heart failure with sinus rhythm has never ceased. although cardiac glycosides are of unquestionable value in tachycardia caused by atrial fibrillation or atrial flutter, the chronic use of these drugs in sinus rhythm is not generally accepted. the development of tolerance has been reported. it is of interest that withering hirnself wrote: "-let it (foxglove) be continued until it either acts on the kidneys, the stomach, the pulse, or the bowels; iet it be stopped upon the first appearance of any of these effects, and i will maintain that the patient will not suffer from its exhibition, nor the practitioner be disappointed in any reasonable expectation. " in west germany alone, more than three million patients (about 5% of the total population) are constantly taking cardiac glycosides. these drugs are the most prescribed medicaments in many countries. thus, we considered it worthwhile and necessary to review in a critical way today's knowledge about the foxglove; to report new findings and to evaluate old statements.

Cardiac Glycoside Receptors and Positive Inotropy Evidence for more than one receptor? Symposium, Munich, October 26–29, 1983

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Author by : E. Erdmann
Languange Used : English, France, Spanish, Italia and chinese
Page : 162
Isbn : 3642723764
Identifier : 9783642723766
Release : 2013-12-21
Publisher by : Steinkopff
Category : Medical
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Description : Read Now Cardiac Glycoside Receptors And Positive Inotropy by E. Erdmann and you can download with pub, pdf, txt, doc, and more file format with free account. symposium, munich, october 26-29, 1983

Some Drugs and Herbal Medicines Iarc Monographs on the Evaluation of Carcinogenic Risks to Humans

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Author by : International Agency for Research on Cancer
Languange Used : English, France, Spanish, Italia and chinese
Page : 434
Isbn : 9789283201465
Identifier : 9283201469
Release : 2016-07-18
Publisher by : no defined
Category :
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Description : Read Now Some Drugs And Herbal Medicines by International Agency for Research on Cancer and you can download with pub, pdf, txt, doc, and more file format with free account. this volume of the "iarc monographs" provides an assessment of the carcinogenicity of 14 drugs and herbal products.the iarc monographs working group relied mainly on epidemiological studies to evaluate the carcinogenic hazard to humans exposed to the drugs digoxin (widely prescribed for the treatment of chronic heart failure), pioglitazone (used for the treatment of type 2 diabetes mellitus), and hydrochlorothiazide (used to treat hypertension).other agents evaluated included the drugs primidone, sulfasalazine, pentosan polysulfate sodium, and triamterene, and five herbal products (or their components): aloe vera whole leaf extract, goldenseal root powder, ginkgo biloba leaf extract, kava extract, and pulegone. in view of the limited agent-specific information available from epidemiological studies, assessments of these agents relied mainly on carcinogenicity bioassays to reach conclusions as to the carcinogenic hazard to exposed humans.

Annual Plant Reviews, Biochemistry of Plant Secondary Metabolism

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Author by : Michael Wink
Languange Used : English, France, Spanish, Italia and chinese
Page : 464
Isbn : 1444347918
Identifier : 9781444347913
Release : 2011-06-13
Publisher by : John Wiley & Sons
Category : Science
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Description : Read Now Annual Plant Reviews Biochemistry Of Plant Secondary Metabolism by Michael Wink and you can download with pub, pdf, txt, doc, and more file format with free account. this brand new annual plant reviews volume is the second edition of the highly successful and well-received annual plant reviews, volume 2. this exciting new volume provides an up-to-date survey of the biochemistry and physiology of plant secondary metabolism. the volume commences with an overview of the biochemistry, physiology and function of secondary metabolism, followed by detailed reviews of the major groups of secondary metabolites: alkaloids and betalains, cyanogenic glucosides, glucosinolates and nonprotein amino acids, phenyl propanoids and related phenolics, terpenoids, cardiac glycosides and saponins. a final chapter discusses the evolution of secondary metabolism. this carefully compiled new edition brings together chapters from some of the world's leading experts in plant secondary metabolism. completely revised and brought right up to date with much new information, this volume is an essential purchase for advanced students, researchers and professionals in biochemistry, physiology, molecular biology, genetics, plant sciences, agriculture, medicine, pharmacology and pharmacy, working in the academic and industrial sectors, including those working in the pesticide and pharmaceutical industries. libraries in all universities and research establishments where these subjects are studied and taught will need copies of this excellent volume on their shelves. a companion volume annual plant reviews volume 39, functions and biotechnology of plant secondary metabolites, second edition, edited by m. wink, is also available.

Cardiac Glycosides

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Author by : G. Bodem
Languange Used : English, France, Spanish, Italia and chinese
Page : 428
Isbn : 3642669042
Identifier : 9783642669040
Release : 2012-12-06
Publisher by : Springer Science & Business Media
Category : Medical
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Description : Read Now Cardiac Glycosides by G. Bodem and you can download with pub, pdf, txt, doc, and more file format with free account. in spite of old vintage and 200 years of clinical use, digitalis remains an interesting therapeutic agent, to clinicians as well as to the pharmacologist, the biochemist, and colleagues in other diciplines of theoretic medicine. when a drug, however, has so many attractive facets, it seems proper and ajvis able for the success of a scientific meeting to focus on a number of well-defined aspects. this symposium was devoted to pharmacokinetics, drug metabolism, analytic procedures, blood level determinations, and their interpretation both for thera peutic and toxic situations. considerable progress has been made during the last years in this area of digitalis research. the time was suitable for a critical reap praisal of facts and theories and for future planning. our main intention was to relate analytic data and biochemical findings to clinical problems and questions. despite the undoubtedly basic character of clinical pharmacology, it is neverthe less an applied science which should help to develop the rational basis of thera peutics. we are particularly grateful to the active participants who bore the burden of preparing presentations and - even worse - manuscripts. at the same time we are well-aware that many other active research groups would have been able to contribute in this way, but our program was limited because of the short time available. their knowledge is included in the discussion parts of the meeting, so we hope a well-balanced description of the present state of affairs emerged in this volume.

Toxicants of Plant Origin Glycosides

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Author by : Peter R. Cheeke
Languange Used : English, France, Spanish, Italia and chinese
Page : 288
Isbn : 9780849369919
Identifier : 0849369916
Release : 1989-07-31
Publisher by : CRC Press
Category : Medical
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Description : Read Now Toxicants Of Plant Origin by Peter R. Cheeke and you can download with pub, pdf, txt, doc, and more file format with free account. this comprehensive treatise offers an in-depth discussion of natural toxicants in plants, emphasizing their effects as defenses against herbivory. coevolution of plants and her-bivores are covered with a detailed treatment of toxicant metabolism and systemic effects in mammalian tissues. con-sideration of the economic importance of plant toxins, modi-fication by plant breeding, management of toxico-sis, and toxicant problems in various geographic areas are in-cluded. each volume offers an extensive description of chemistry, biosynthesis, analysis, distribution in plants, metabolism in mam-mals and insects, and practical problems in humans and livestock.

An Account of the Foxglove

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Author by : William Withering
Languange Used : English, France, Spanish, Italia and chinese
Page : 148
Isbn : 3732662721
Identifier : 9783732662722
Release : 2018-04-06
Publisher by : BoD – Books on Demand
Category : Fiction
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Description : Read Now An Account Of The Foxglove by William Withering and you can download with pub, pdf, txt, doc, and more file format with free account. reproduction of the original: an account of the foxglove by william withering