Cardiac Glycosides Part I

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Cardiac Glycosides Part I: Experimental Pharmacology

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Author by : Kurt Greeff
Languange Used : English, France, Spanish, Italia and chinese
Page : 682
Isbn : 3642681638
Identifier : 9783642681639
Release : 2012-12-06
Publisher by : Springer Science & Business Media
Category : Medical
Total Download : 1444006
Total Read : 8446018
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Description : Read Now Cardiac Glycosides by Kurt Greeff and you can download with pub, pdf, txt, doc, and more file format with free account. following the monographs by straub (1924) and lendle (1935), this is the third contribution to the "pharmacology of cardiac glycosides" within the handbook of experimental pharmacology, which was founded by arthur heffter and con tinued by wolfgang heubner. because of the need created by the length of time that had elapsed since lendle's work, the editorial board requested the rapid ap pearance of this 56th volume, which represents current knowledge of the pharma cology and clinical pharmacology of cardiac glycosides. in order to avoid any delay, numerous authors were invited to contribute because shorter contributions take less time to prepare and are consequently more up-to-date. the disadvantage is that some overlap between certain chapters could not be avoided, despite the editor's efforts. overlapping can, however, actually be useful, in that differing opinions may be provided and topical issues discussed from varying viewpoints. this re minds the reader that scientific horizons in medicine should often be widened or revised. i would like to thank dr. alanna fox and dr. k. anantharaman for their help and advice in the revision of certain chapters. i am also grateful to springer verlag, and particularly to mr. winstanley and mr. emerson, for their contribu tion to the completion of this volume through translation and corrections. in con clusion i would like to thank mrs. walker, mr. bischoff, mrs. seeker, and mr. bergstedt of springer-verlag for their helpful support.

Cardiac Glycosides Part II: Pharmacokinetics and Clinical Pharmacology

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Author by :
Languange Used : English, France, Spanish, Italia and chinese
Page : 394
Isbn : 3642681662
Identifier : 9783642681660
Release : 2012-12-06
Publisher by : Springer Science & Business Media
Category : Medical
Total Download : 5547777
Total Read : 4518555
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Description : Read Now Cardiac Glycosides by and you can download with pub, pdf, txt, doc, and more file format with free account. the pharmacokinetics of digitalis glycosides have been the subject of extensive re view (iisalo, 1977; aronson, 1980; perrier et ai., 1977). research on glycoside kinetics has progressed at a rapid pace, requiring continuing reevaluation of the state of our understanding of this problem. the present article focuses on the effect of disease states (renal, gastrointestinal, thyroid, and cardiac) on the absorption, distribution, and clearance of a number of digitalis glycosides. evidence is critically reviewed, and interpreted with respect to possible clinical implications. a. renal insufficiency i. strophanthin strophanthin disposition in renal failure has been evaluated in only two studies. kramer et ai. (1970) determined an elimination half-life of 14 h in normals as com pared to 60 h in anuric patients. similar results were reported by brass and pm lipps (1970) using tritiated strophanthin. they found a half-life value of 18 h in healthy individuals as compared to 68 h in anuric patients. the findings clearly in dicate that the elimination half-life of strophanthin is prolonged in renal failure.

Cardiac Glycosides Part I. Apocynaceae : the Genera Carissa L., Vallaris Burm. F., Beaumontia Wall., Anodendron A. DC., and Others

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Author by : Norman Grainger Bisset
Languange Used : English, France, Spanish, Italia and chinese
Page : 18
Isbn :
Identifier : OCLC:222551735
Release : 1957
Publisher by :
Category : Cardiac glycosides
Total Download : 2006399
Total Read : 7737513
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Cardiac Glycosides 1785–1985 Biochemistry — Pharmacology — Clinical Relevance

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Author by : E. Erdmann, K. Greeff, J.C. Skou
Languange Used : English, France, Spanish, Italia and chinese
Page : 552
Isbn : 3662112922
Identifier : 9783662112922
Release : 2013-06-29
Publisher by : Springer Science & Business Media
Category : Medical
Total Download : 8087960
Total Read : 8621100
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Description : Read Now Cardiac Glycosides 1785 1985 by E. Erdmann, K. Greeff, J.C. Skou and you can download with pub, pdf, txt, doc, and more file format with free account. the bicentenary of william withering's now famous medical report entitled "an account of the foxglove and some of its medical uses" has given us the occasion to analyze the state of the art. cardiac glycosides in 1985 are considered tobe the basis for medical treatment of myocardial failure, together with diuretics and vasodilators in the more severe cases. nevertheless, the controversy as to their exact place in the treatment of heart failure with sinus rhythm has never ceased. although cardiac glycosides are of unquestionable value in tachycardia caused by atrial fibrillation or atrial flutter, the chronic use of these drugs in sinus rhythm is not generally accepted. the development of tolerance has been reported. it is of interest that withering hirnself wrote: "-let it (foxglove) be continued until it either acts on the kidneys, the stomach, the pulse, or the bowels; iet it be stopped upon the first appearance of any of these effects, and i will maintain that the patient will not suffer from its exhibition, nor the practitioner be disappointed in any reasonable expectation. " in west germany alone, more than three million patients (about 5% of the total population) are constantly taking cardiac glycosides. these drugs are the most prescribed medicaments in many countries. thus, we considered it worthwhile and necessary to review in a critical way today's knowledge about the foxglove; to report new findings and to evaluate old statements.

Cardiac Glycosides 1785–1985 Biochemistry — Pharmacology — Clinical Relevance

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Author by : E. Erdmann, K. Greeff, J.C. Skou
Languange Used : English, France, Spanish, Italia and chinese
Page : 552
Isbn : 3662112922
Identifier : 9783662112922
Release : 2013-06-29
Publisher by : Springer Science & Business Media
Category : Medical
Total Download : 9511561
Total Read : 8391401
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Description : Read Now Cardiac Glycosides 1785 1985 by E. Erdmann, K. Greeff, J.C. Skou and you can download with pub, pdf, txt, doc, and more file format with free account. the bicentenary of william withering's now famous medical report entitled "an account of the foxglove and some of its medical uses" has given us the occasion to analyze the state of the art. cardiac glycosides in 1985 are considered tobe the basis for medical treatment of myocardial failure, together with diuretics and vasodilators in the more severe cases. nevertheless, the controversy as to their exact place in the treatment of heart failure with sinus rhythm has never ceased. although cardiac glycosides are of unquestionable value in tachycardia caused by atrial fibrillation or atrial flutter, the chronic use of these drugs in sinus rhythm is not generally accepted. the development of tolerance has been reported. it is of interest that withering hirnself wrote: "-let it (foxglove) be continued until it either acts on the kidneys, the stomach, the pulse, or the bowels; iet it be stopped upon the first appearance of any of these effects, and i will maintain that the patient will not suffer from its exhibition, nor the practitioner be disappointed in any reasonable expectation. " in west germany alone, more than three million patients (about 5% of the total population) are constantly taking cardiac glycosides. these drugs are the most prescribed medicaments in many countries. thus, we considered it worthwhile and necessary to review in a critical way today's knowledge about the foxglove; to report new findings and to evaluate old statements.

An Account of the Foxglove, and Some of Its Medical Uses With Practical Remarks on Dropsy and Other Diseases

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Author by : William Withering
Languange Used : English, France, Spanish, Italia and chinese
Page : 207
Isbn :
Identifier : UOM:39015029859629
Release : 1785
Publisher by :
Category : Digitalis
Total Download : 4094692
Total Read : 7507868
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Cardiac Glycoside Receptors and Positive Inotropy Evidence for more than one receptor? Symposium, Munich, October 26–29, 1983

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Author by : E. Erdmann
Languange Used : English, France, Spanish, Italia and chinese
Page : 162
Isbn : 3642723764
Identifier : 9783642723766
Release : 2013-12-21
Publisher by : Steinkopff
Category : Medical
Total Download : 5197199
Total Read : 3292524
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Toxicants of Plant Origin Glycosides

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Author by : Peter R. Cheeke
Languange Used : English, France, Spanish, Italia and chinese
Page : 288
Isbn : 9780849369919
Identifier : 0849369916
Release : 1989-07-31
Publisher by : CRC Press
Category : Medical
Total Download : 6487492
Total Read : 8937903
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Description : Read Now Toxicants Of Plant Origin by Peter R. Cheeke and you can download with pub, pdf, txt, doc, and more file format with free account. this comprehensive treatise offers an in-depth discussion of natural toxicants in plants, emphasizing their effects as defenses against herbivory. coevolution of plants and her-bivores are covered with a detailed treatment of toxicant metabolism and systemic effects in mammalian tissues. con-sideration of the economic importance of plant toxins, modi-fication by plant breeding, management of toxico-sis, and toxicant problems in various geographic areas are in-cluded. each volume offers an extensive description of chemistry, biosynthesis, analysis, distribution in plants, metabolism in mam-mals and insects, and practical problems in humans and livestock.

Cardiac Glycosides: Pharmacokinetics and clinical pharmacology

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Author by :
Languange Used : English, France, Spanish, Italia and chinese
Page :
Isbn :
Identifier : OCLC:7957792
Release : 1981
Publisher by :
Category : Cardiac glycosides
Total Download : 7170411
Total Read : 600120
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Havard's Nursing Guide to Drugs - Mobile optimised site

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Author by : Adriana P. Tiziani
Languange Used : English, France, Spanish, Italia and chinese
Page : 1352
Isbn : 0729586057
Identifier : 9780729586054
Release : 2017-05-24
Publisher by : Elsevier Health Sciences
Category : Medical
Total Download : 3332713
Total Read : 3787596
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Description : Read Now Havard S Nursing Guide To Drugs Mobile Optimised Site by Adriana P. Tiziani and you can download with pub, pdf, txt, doc, and more file format with free account. the premier drug guide for nurses and midwives since 1983. now in its 10th edition, havard's nursing guide to drugs continues to provide reliable, accurate drug information for nursing and midwifery students and practitioners. this user-friendly drug guide delivers safe, up-to-date drug administration information regarding form, action, use, dose, adverse effects and interactions in compliance with current pharmaceutical guidelines from the therapeutic goods administration and mims. nursing points and cautions highlight best practice in drug administration and expanded focus on patient teaching and advice ensures quality patient care. all drugs listed by therapeutic class and by body system both trade names and generic drug names are provided icons indicate cautions for drugs used during pregnancy and breastfeeding, and drug specific restrictions in sport a quick reference guide for calculating drug dosages and drip rates common abbreviations, units and concentrations appendix 3 features the latest mims updates, including dual labelling of drug ingredients to demonstrate international alignment fully revised section on antineoplastic agents new drugs added to immunomodifiers, pulmonary arterial hypertension agents and eye, ear and nose companion mobile optimised site available as a separate purchase or comprehensive package: - provides easy online access to the trusted drug guide - search by body system, therapeutic class or both - perfect support for students and practitioners during study or clinical practice

Cardiac Glycosides

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Author by : G. Bodem, H. J. Dengler
Languange Used : English, France, Spanish, Italia and chinese
Page : 428
Isbn : 3642669042
Identifier : 9783642669040
Release : 2012-12-06
Publisher by : Springer Science & Business Media
Category : Medical
Total Download : 6883265
Total Read : 9082767
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Description : Read Now Cardiac Glycosides by G. Bodem, H. J. Dengler and you can download with pub, pdf, txt, doc, and more file format with free account. in spite of old vintage and 200 years of clinical use, digitalis remains an interesting therapeutic agent, to clinicians as well as to the pharmacologist, the biochemist, and colleagues in other diciplines of theoretic medicine. when a drug, however, has so many attractive facets, it seems proper and ajvis able for the success of a scientific meeting to focus on a number of well-defined aspects. this symposium was devoted to pharmacokinetics, drug metabolism, analytic procedures, blood level determinations, and their interpretation both for thera peutic and toxic situations. considerable progress has been made during the last years in this area of digitalis research. the time was suitable for a critical reap praisal of facts and theories and for future planning. our main intention was to relate analytic data and biochemical findings to clinical problems and questions. despite the undoubtedly basic character of clinical pharmacology, it is neverthe less an applied science which should help to develop the rational basis of thera peutics. we are particularly grateful to the active participants who bore the burden of preparing presentations and - even worse - manuscripts. at the same time we are well-aware that many other active research groups would have been able to contribute in this way, but our program was limited because of the short time available. their knowledge is included in the discussion parts of the meeting, so we hope a well-balanced description of the present state of affairs emerged in this volume.

Cardiac Glycosides 1785-1985 Biochemistry, Pharmacology, Clinical Relevance

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Author by : Erland Erdmann, K. Greeff, J. C. Skou
Languange Used : English, France, Spanish, Italia and chinese
Page : 552
Isbn :
Identifier : UCAL:B5040174
Release : 1986-01-01
Publisher by : Springer Science & Business Media
Category : Cardiac glycosides
Total Download : 2022105
Total Read : 6790902
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Annual Plant Reviews, Biochemistry of Plant Secondary Metabolism

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Author by : Michael Wink
Languange Used : English, France, Spanish, Italia and chinese
Page : 464
Isbn : 1444347918
Identifier : 9781444347913
Release : 2011-06-13
Publisher by : John Wiley & Sons
Category : Science
Total Download : 2387173
Total Read : 7836556
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Description : Read Now Annual Plant Reviews Biochemistry Of Plant Secondary Metabolism by Michael Wink and you can download with pub, pdf, txt, doc, and more file format with free account. this brand new annual plant reviews volume is the second edition of the highly successful and well-received annual plant reviews, volume 2. this exciting new volume provides an up-to-date survey of the biochemistry and physiology of plant secondary metabolism. the volume commences with an overview of the biochemistry, physiology and function of secondary metabolism, followed by detailed reviews of the major groups of secondary metabolites: alkaloids and betalains, cyanogenic glucosides, glucosinolates and nonprotein amino acids, phenyl propanoids and related phenolics, terpenoids, cardiac glycosides and saponins. a final chapter discusses the evolution of secondary metabolism. this carefully compiled new edition brings together chapters from some of the world's leading experts in plant secondary metabolism. completely revised and brought right up to date with much new information, this volume is an essential purchase for advanced students, researchers and professionals in biochemistry, physiology, molecular biology, genetics, plant sciences, agriculture, medicine, pharmacology and pharmacy, working in the academic and industrial sectors, including those working in the pesticide and pharmaceutical industries. libraries in all universities and research establishments where these subjects are studied and taught will need copies of this excellent volume on their shelves. a companion volume annual plant reviews volume 39, functions and biotechnology of plant secondary metabolites, second edition, edited by m. wink, is also available.

Meyler's Side Effects of Herbal Medicines

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Author by : J. K. Aronson
Languange Used : English, France, Spanish, Italia and chinese
Page : 303
Isbn : 0444532692
Identifier : 9780444532695
Release : 2009
Publisher by : Elsevier
Category : Medical
Total Download : 5121281
Total Read : 4139913
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Description : Read Now Meyler S Side Effects Of Herbal Medicines by J. K. Aronson and you can download with pub, pdf, txt, doc, and more file format with free account. "this book summarizes the adverse effects of a large range of herbal medicines and the active ingredients that they contain. it includes extensive lists of the families of plants that are used as herbal medicines, including the latin names of genera and species as well as the common names of individual plants. the material is drawn from the 15th edition of the internationally renowned encyclopedia, meyler's side effects of drugs: the encyclopedia of adverse drug reactions and interactions, and the latest volumes in the companion series, side effects of drugs annuals."--book jacket.

A Survey of Cardiac Glycosides and Genins

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Author by : John Hampton Hoch
Languange Used : English, France, Spanish, Italia and chinese
Page : 93
Isbn :
Identifier : UOM:39015009545800
Release : 1961
Publisher by :
Category : Glycosides
Total Download : 5903594
Total Read : 9383435
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The Sodium Pump Structure Mechanism, Hormonal Control and its Role in Disease

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Author by : Ernst Bamberg, Wilhelm Schoner
Languange Used : English, France, Spanish, Italia and chinese
Page : 906
Isbn : 3642725112
Identifier : 9783642725111
Release : 2012-12-06
Publisher by : Springer Science & Business Media
Category : Medical
Total Download : 9709099
Total Read : 460178
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Description : Read Now The Sodium Pump by Ernst Bamberg, Wilhelm Schoner and you can download with pub, pdf, txt, doc, and more file format with free account. the sodium of animal cell membranes converts the chemical energy obtained from the hydrolysis of adenosine 5' -triphosphate into a movement of the cations na + and k + against an electrochemical gradient. the gradient is used subse quently as an energy source to drive the uptake of metabolic substrates in polar epithelial cells and to use it for purposes of communications in excitable cells. the biological importance of the sodium pump is evident from the fact that be tween 20-70% of the cell's metabolic energy is consumed for the pumping pro cess. moreover, the sodium pump is an important biological system involved in regulatory processes like the maintenance of the cells' and organism's water me tabolism. it is therefore understandable that special cellular demands are han dled better by special isoforms of the sodium pump, that the expression of the sodium pump and their isoforms is regulated by hormones as is the activity of the sodium pump via hormone-regulated protein kinases. additionally, the sodium pump itself seems to be a receptor for a putative new group of hormones, the endogenous digitalis-like substances, which still have to be defined in most cases in their structure. this group of substances has its chemically well known coun terpart in steroids from plant and toad origin which are generally known as "car diac glycosides". they are in medical use since at least 200 years in medicine in the treatment of heart diseases.