Cellular And Molecular Pathobiology Of Cardiovascular Disease

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Cellular and Molecular Pathobiology of Cardiovascular Disease

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Author by : Monte Willis
Languange Used : English, France, Spanish, Italia and chinese
Page : 338
Isbn : 0124055257
Identifier : 9780124055254
Release : 2013-12-23
Publisher by : Academic Press
Category : Science
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Description : Read Now Cellular And Molecular Pathobiology Of Cardiovascular Disease by Monte Willis and you can download with pub, pdf, txt, doc, and more file format with free account. cellular and molecular pathobiology of cardiovascular disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. this book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for phd trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. no other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. the text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. it is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. explains how to identify cardiovascular pathologies and compare with normal physiology to aid research gives concise explanations of key issues and background reading suggestions covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology

Endocrinology of the Heart in Health and Disease Integrated, Cellular, and Molecular Endocrinology of the Heart

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Author by : Jonathan C. Schisler
Languange Used : English, France, Spanish, Italia and chinese
Page : 378
Isbn : 0128031123
Identifier : 9780128031124
Release : 2016-10-19
Publisher by : Academic Press
Category : Medical
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Description : Read Now Endocrinology Of The Heart In Health And Disease by Jonathan C. Schisler and you can download with pub, pdf, txt, doc, and more file format with free account. endocrinology of the heart in health and disease: integrated, cellular, and molecular endocrinology of the heart covers the traditional concepts of cardio-endocrinology, the role of the various hormone systems, both in health and disease, therapeutic implications, and other recent advances in the various fields represented. the book explores how cardiac hormones are changed in various cardiac pathologies and the recent success that has been uncovered in their therapeutic use. additional focus is placed on how the heart responds both physiologically and pathophysiologically to a plethora of circulating hormones, reinforcing the importance of the heart as a target of numerous endocrine systems, such as the brain, renal, and adipose. significant advances have come from basic, clinical, and translational research from a multiplicity of investigators with diverse backgrounds. the book features over 200 photomicrographs, diagrams of molecular relationships, and tables that complement and support the text. it is aimed at a wide audience, including graduate students and post-doctoral fellows in a wide array of biomedical departments and phd programs (e.g. pathology, physiology, genetics, pharmacology, molecular biology, and cell biology) related to the endocrine and cardiovascular sciences curricula, as well as medical residents in pathology, laboratory medicine, internal medicine, and cardiology. develops the concept of the heart as both an endocrine organ and an endocrine target, exploring the endocrine function of the heart in both health and disease explains how the levels of several cardiac hormones are changed in various cardiac pathologies and how some hormones can be used therapeutically offers a single resource on cardio-endocrine disease which collates and curates the wide range of advances being made in the areas of molecular biology, biochemistry, physiology, and pathology

Molecular Pathology The Molecular Basis of Human Disease

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Author by : William B. Coleman
Languange Used : English, France, Spanish, Italia and chinese
Page : 664
Isbn : 9780123859129
Identifier : 0123859123
Release : 2009-03-10
Publisher by : Academic Press
Category : Science
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Description : Read Now Molecular Pathology by William B. Coleman and you can download with pub, pdf, txt, doc, and more file format with free account. molecular pathology: the molecular basis of human disease provides a current and comprehensive view of the molecular basis and mechanisms of human disease. combining accepted principles with broader theoretical concepts and with contributions from a group of experts, the book looks into disease processes in the context of traditional pathology and their implications for translational molecular medicine. it also discusses concepts in molecular biology and genetics, recent scientific and technological advances in modern pathology, the concept of ""molecular pathogenesis"" of disease, and how disease evolves from normal cells and tissues due to perturbations in molecular pathways. the book describes the integration of molecular and cellular pathogenesis using a bioinformatics approach and a systems biology approach to disease pathogenesis. it also discusses current and future strategies in molecular diagnosis of human disease, and the impact of molecular diagnosis on treatment decisions and the practice of personalized medicine. this book is a valuable resource for students, biomedical researchers, practicing physician-scientists who undertake disease-related basic science and translational research, and pathology residents and other postdoctoral fellows. * exam master® web site will host "self-assessment" questions that students can use to study for the molecular section of the board exam * companion web site – will host a complete set of powerpoint slides: to include images from the book and additional images for teaching; course materials; lecture materials * teaches from the perspective of “integrative systems biology, which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease * outlines the principles and practice of molecular pathology * explains the practice of “molecular medicine and the translational aspects of molecular pathology

Molecular and Translational Vascular Medicine

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Author by : Jonathon W. Homeister
Languange Used : English, France, Spanish, Italia and chinese
Page : 338
Isbn : 1617799068
Identifier : 9781617799068
Release : 2012-06-28
Publisher by : Springer Science & Business Media
Category : Medical
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Description : Read Now Molecular And Translational Vascular Medicine by Jonathon W. Homeister and you can download with pub, pdf, txt, doc, and more file format with free account. molecular and translational vascular medicine will serve as a state-of-the-art resource for physicians and translational medical researchers alike who are interested in the rapidly evolving field of vascular medicine. the text provides new insight into the basic mechanisms of classic vascular pathophysiologic processes like angiogenesis, atherosclerosis, thrombosis, and vasculitis. furthermore, it covers new areas of investigation including the role of the ubiquitin proteasome system in vascular disease, endothelial progenitor cells for disease treatment, and the genetic basis of thoracic aortic aneurysms. lastly, this volume includes sections on the newly emerging field of therapeutic angiogenesis, and the developing technology of nanoparticle-based imaging and therapeutic treatment of the diseased vasculature. all chapters are written by established experts in their fields, including pathologists, cardiovascular surgeons, and internists as well as translational biomedical researchers in a wide range of disciplines. while comprehensive, the material is presented in a manner that simplifies the complex pathophysiologic mechanisms that underlie common vascular diseases. molecular and translational vascular medicine will be of great value to a broad audience including internists, cardiovascular and vascular surgeons, pathologists, residents and fellows, as well as translational biomedical researchers.

Cardiovascular Diseases Nutritional and Therapeutic Interventions

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Author by : Nilanjana Maulik, Ph.D.
Languange Used : English, France, Spanish, Italia and chinese
Page : 614
Isbn : 1439882002
Identifier : 9781439882009
Release : 2013-04-09
Publisher by : CRC Press
Category : Medical
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Description : Read Now Cardiovascular Diseases by Nilanjana Maulik, Ph.D. and you can download with pub, pdf, txt, doc, and more file format with free account. with cardiovascular disease remaining one of the primary causes of morbidity and mortality worldwide, there is a great need to further understand the molecular basis of this disease class and develop new therapeutic or preventative measures. cardiovascular diseases: nutritional and therapeutic interventions presents up-to-date information on the pathobiology of cardiovascular diseases, emphasizing emerging therapeutics and nutritional interventions. the book is divided into four parts: epidemiology, epigenetics, pathobiology, and therapies for cardiovascular diseases. part i details epidemiological studies, highlighting the extent of the clinical problem. part ii describes the genetic and, primarily, epigenetic modifications associated with cardiovascular disease, including the importance of dna methylation status and the possibility of early intervention using simple dietary modifications. the text also discusses histone modifications associated with disease and potential therapeutic synthetic and dietary compounds such as resveratrol and garlic. covering the etiology and pathobiology, part iii discusses lipid regulation, micro-rnas, emerging cell-based therapies, and new receptor targets for therapeutics as well as targeted imaging. it also describes the link between cancer therapies and cardiomyopathy and the potential of vitamin c to ameliorate this effect. part iv focuses on therapeutic and nutritional interventions, namely, stem cell therapies, emerging nanomedicines, and a wide range of dietary interventions. these include general healthy diets, fruits and vegetables, botanicals, effects of specific compounds such as antioxidants, and discussions on garlic, curcumin, and resveratrol. the text also covers lifestyle factors, emphasizing the importance of stress in the occurrence of and meditation and yoga in the management of cardiovascular disease. this book provides a comprehensive reference for clinicians and scientists, combining epidemiology, prevention, and modern treatment strategies.

Pathobiology of Human Disease

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Author by : Linda M. Mcmanus
Languange Used : English, France, Spanish, Italia and chinese
Page : 5000
Isbn : 9780123864567
Identifier : 0123864569
Release : 2014-08-01
Publisher by : Academic Press
Category : Medical
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Description : Read Now Pathobiology Of Human Disease by Linda M. Mcmanus and you can download with pub, pdf, txt, doc, and more file format with free account. pathobiology of human disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. the work spans more than 48 different biological and medical fields, in five basic sections: human organ systems molecular pathology/basic mechanisms of diseases animal models/other model systems experimental pathology clinical pathology each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of "normal" and "disease" anatomy and histology images fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions

Cardiovascular Pathology

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Author by : L. Maximilian Buja
Languange Used : English, France, Spanish, Italia and chinese
Page : 830
Isbn : 0128004592
Identifier : 9780128004593
Release : 2015-11-11
Publisher by : Academic Press
Category : Science
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Description : Read Now Cardiovascular Pathology by L. Maximilian Buja and you can download with pub, pdf, txt, doc, and more file format with free account. cardiovascular pathology, fourth edition, provides users with a comprehensive overview that encompasses its examination, cardiac structure, both normal and physiologically altered, and a multitude of abnormalities. this updated edition offers current views on interventions, both medical and surgical, and the pathology related to them. congenital heart disease and its pathobiology are covered in some depth, as are vasculitis and neoplasias. each section has been revised to reflect new discoveries in clinical and molecular pathology, with new chapters updated and written with a practical approach, especially with regards to the discussion of pathophysiology. new chapters reflect recent technological advances with cardiac devices, transplants, genetics, and immunology. each chapter is highly illustrated and covers contemporary aspects of the disease processes, including a section on the role of molecular diagnostics and cytogenetics as specifically related to cardiovascular pathology. customers buy the print + electronic product together! serves as a contemporary, all-inclusive guide to cardiovascular pathology for clinicians and researchers, as well as clinical residents and fellows of pathology, cardiology, cardiac surgery, and internal medicine offers new organization of each chapter to enable uniformity for learning and reference: definition, epidemiology, clinical presentation, pathogenesis/genetics, light and electron microscopy/immunohistochemistry, differential diagnosis, treatment and potential complications features six new chapters and expanded coverage of the normal heart and blood vessels, cardiovascular devices, congenital heart disease, tropical and infectious cardiac disease, and forensic pathology of the cardiovascular system contains 400+ full color illustrations and an online image collection facilitate research, study, and lecture slide creation

Translational Cardiology Molecular Basis of Cardiac Metabolism, Cardiac Remodeling, Translational Therapies and Imaging Techniques

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Author by : Cam Patterson
Languange Used : English, France, Spanish, Italia and chinese
Page : 544
Isbn : 1617798916
Identifier : 9781617798917
Release : 2012-07-04
Publisher by : Springer Science & Business Media
Category : Medical
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Description : Read Now Translational Cardiology by Cam Patterson and you can download with pub, pdf, txt, doc, and more file format with free account. translational cardiology: molecular basis of cardiac metabolism, cardiac remodeling, translational therapies and imaging techniques provides an up-to-date introduction to the role circadian rhythms, cardiac plasticity, and mechanotransduction play in the heart, while at the same time introducing new developments in cellular, viral, and non-biologic therapies that are in the process of being developed. importantly, the focus of this book is on topics that, due to their novelty, are largely not covered in the other major textbooks. a special emphasis is placed on the molecular basis of cardiac metabolism, new concepts in cardiac remodeling, and translational therapies and imaging techniques currently under development for clinical use. the chapters are written by experts from diverse clinical and biomedical research backgrounds. translational cardiology: molecular basis of cardiac metabolism, cardiac remodeling, translational therapies and imaging techniques simplifies the complexity of the molecular basis of disease by focusing on patient-oriented disease mechanisms and therapies and is of great value to a broad audience including physicians (e.g. cardiologists, cardiovascular surgeons, pathologists) as well as translational biomedical researchers in a wide range of disciplines.

Molecular Basis of Cardiovascular Diseases: Implications of Natriuretic Peptides

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Author by : Speranza Rubattu
Languange Used : English, France, Spanish, Italia and chinese
Page : 212
Isbn : 3039215825
Identifier : 9783039215829
Release : 2019-10-21
Publisher by : MDPI
Category : Science
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Description : Read Now Molecular Basis Of Cardiovascular Diseases Implications Of Natriuretic Peptides by Speranza Rubattu and you can download with pub, pdf, txt, doc, and more file format with free account. the natriuretic peptides (nps) family includes a class of hormones and their receptors needed for the physiological control of cardiovascular functions. the discovery of nps provided a fundamental contribution into our understanding of the physiological regulation of blood pressure, and of heart and kidney functions. nps have also been implicated in the pathogenesis of several cardiovascular diseases (cvds), including hypertension, atherosclerosis, heart failure, and stroke. a fine comprehension of the molecular mechanisms dependent from nps and underlying the promotion of cardiovascular damage has contributed to improve our understanding of the molecular basis of all major cvds. finally, the opportunity to target nps in order to develop new therapeutic tools for a better treatment of cvds has been developed over the years. the current special issue of the journal covers all major aspects of the molecular implications of nps in physiology and pathology of the cardiovascular system, including np-based therapeutic approaches.

Nitric Oxide Biology and Pathobiology

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Author by : Louis J. Ignarro
Languange Used : English, France, Spanish, Italia and chinese
Page : 1017
Isbn : 9780080525037
Identifier : 0080525032
Release : 2000-09-13
Publisher by : Academic Press
Category : Science
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Description : Read Now Nitric Oxide by Louis J. Ignarro and you can download with pub, pdf, txt, doc, and more file format with free account. nitric oxide (no) is a gas that transmits signals in an organism. signal transmission by a gas that is produced by one cell and which penetrates through membranes and regulates the function of another cell represents an entirely new principle for signaling in biological systems. no is a signal molecule of key importance for the cardiovascular system acting as a regulator of blood pressure and as a gatekeeper of blood flow to different organs. no also exerts a series of other functions, such as acting a signal molecule in the nervous system and as a weapon against infections. no is present in most living creatures and made by many different types of cells. no research has led to new treatments for treating heart as well as lung diseases, shock, and impotence. scientists are currently testing whether no can be used to stop the growth of cancerous tumors, since the gas can induce programmed cell death, apoptosis. this book is the first comprehensive text on nitric oxide to cover all aspects--basic biology, chemistry, pathobiology, effects on various disease states, and therapeutic implications. edited by nobel laureate louis j. ignarro, editor of the academic press journal, nitric oxide authored by world experts on nitric oxide includes an overview of basic principles of biology and chemical biology covers principles of pathobiology, including the nervous system, cardiovascular function, pulmonary function, and immune defense

Microcirculation

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Author by : Ronald F. Tuma
Languange Used : English, France, Spanish, Italia and chinese
Page : 1000
Isbn : 9780080569932
Identifier : 0080569935
Release : 2011-04-28
Publisher by : Academic Press
Category : Science
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Description : Read Now Microcirculation by Ronald F. Tuma and you can download with pub, pdf, txt, doc, and more file format with free account. this reference is a volume in the handbook of physiology, co-published with the american physiological society. growth in knowledge about the microcirculation has been explosive with the field becoming fragmented into numerous subdisciplines and subspecialties. this volume pulls all of the critical information into one volume. meticulously edited and reviewed. benefit: provides investigators a unique tool to explore the significance of their findings in the context of other aspects of the microcirculation. in this way, the updated edition has a direct role in helping to develop new pathways of research and scholarship highlights the explosive growth in knowledge about the microcirculation including the biology of nitric oxide synthase (nos), endothelial cell signaling, angiogenesis, cell adhesion molecules, lymphocyte trafficking, ion channels and receptors, and propagated vasomotor responses. benefit: microcirculatory biology has become fragmented into numerous sub-disciplines and subspecialties, and these reference reintegrates the information in one volume

Pathophysiology and Pharmacotherapy of Cardiovascular Disease

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Author by : Gowraganahalli Jagadeesh
Languange Used : English, France, Spanish, Italia and chinese
Page : 1342
Isbn : 3319159615
Identifier : 9783319159614
Release : 2015-05-06
Publisher by : Springer
Category : Medical
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Description : Read Now Pathophysiology And Pharmacotherapy Of Cardiovascular Disease by Gowraganahalli Jagadeesh and you can download with pub, pdf, txt, doc, and more file format with free account. the present book covers the basic principles of cardiovascular physiology, pathophysiology and advanced pharmacology with particular emphasis on cellular mechanisms of drug action. it provides an update on the progress made in several aspects of cardiovascular diseases so that it might kindle scientists and clinicians alike in furthering basic and translational research. in addition, the book is expected to fill imperative gaps in understanding and optimally treating cardiovascular disease.