Doves Diplomats And Diabetes A Darwinian Interpretation Of Type 2 Diabetes And Related Disorders

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Doves, Diplomats, and Diabetes A Darwinian Interpretation of Type 2 Diabetes and Related Disorders

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Author by : Milind Watve
Languange Used : English, France, Spanish, Italia and chinese
Page : 380
Isbn : 1461444098
Identifier : 9781461444091
Release : 2012-08-30
Publisher by : Springer Science & Business Media
Category : Science
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Description : Read Now Doves Diplomats And Diabetes by Milind Watve and you can download with pub, pdf, txt, doc, and more file format with free account. darwinian medicine looks at the ecological and evolutionary roots of disease. a disease is an interaction between a genome and its biotic or abiotic environment and therefore a disease is essentially an ecological process. good understanding of ecology and a darwinian way of thinking can give us novel and useful perspectives on health and disease. if we understand the disease process better, we can certainly prevent, control as well as treat diseases in a better way. although the thought that the origins of obesity and type 2 diabetes (t2d) might lie in our hunter gatherer adaptations is not new, research over the last decade makes us rethink many of the classical concepts. brain and behavior is increasingly being recognized as central to all the endocrine, metabolic and immunological changes that earmark type 2 diabetes and other metabolic syndrome disorders. a major change in paradigm appears to be on the horizon and the proposed book intends to speed up the paradigm shift by raising important questions, pointing out flaws and inadequacies in the prevalent paradigm and stimulating radical rethinking which would redirect and refine the line of research as well as bring some fundamental changes in drug discovery and clinical practice. ​

Bridging the Communication Gap in Science and Technology Lessons from India

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Author by : Pallava Bagla
Languange Used : English, France, Spanish, Italia and chinese
Page : 324
Isbn : 9811010250
Identifier : 9789811010255
Release : 2017-02-17
Publisher by : Springer
Category : Language Arts & Disciplines
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Description : Read Now Bridging The Communication Gap In Science And Technology by Pallava Bagla and you can download with pub, pdf, txt, doc, and more file format with free account. this first-of-a-kind volume provides a snapshot of existing science communication policy and practice in india across different s&t sectors, and offers solutions to building effective communication. it provides an understanding on how to avoid societal clashes in situations when science meets the public in these sectors. the editors and contributors argue that effective s&t communication leads not only to a more informed public but also benefits research itself, and in a changing society like india this is a crucial element related to good governance and policy making. in this volume, experienced masters of the craft provide practical solutions to making s&t communication more effective in a vast democracy like india, which has complex issues related to literacy levels, diverse languages, varying political will, reach, and resources. through, discussions on cases of creating information modules for the public on the internet, television and radio, social media, as well a s traditional ways of outreach like people’s science movements, holding popular science events, and fairs, the volume provides highly valuable directions on how developing countries with low resources and complex populations can communicate s&t research to the public and bridge communication gaps. this volume will interest researchers from science, social science, mass communication and public relations departments, journalists, as well as practitioners and policy makers from government and non-government institutions involved in s&t policy, practice and communication and people who want to understand the complex s&t landscape of india.

Mechanisms of Vascular Defects in Diabetes Mellitus

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Author by : C.C. Kartha
Languange Used : English, France, Spanish, Italia and chinese
Page : 579
Isbn : 3319603248
Identifier : 9783319603247
Release : 2017-08-01
Publisher by : Springer
Category : Science
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Description : Read Now Mechanisms Of Vascular Defects In Diabetes Mellitus by C.C. Kartha and you can download with pub, pdf, txt, doc, and more file format with free account. this book intends to bring together, a panel of renowned experts in the field of vascular biology and diabetology, to integrate the current understanding of the pathogenesis and pathophysiology of vascular diseases in diabetes mellitus. this attempt is significant given the increasing interest in this area as the prevalence of vascular diseases continues to escalate globally. patients with diabetes are at a higher risk of structural and functional changes in all vessel walls of the human body. vascular complications of diabetes are leading causes for both morbidity and mortality. in recent years, several articles have focused on advancing our knowledge on the profound effect of hyperglycemia and insulin resistance on building up vascular wall inflammation leading to endothelial dysfunction in patients with diabetes mellitus other reports have elaborated on the various disorders, hyperglycemia can lead to, their therapies, adverse effects and complications. there are also studies that highlight the role of factors that induce vascular wall alterations in hyperglycemia. in this book, we attempt to discuss vascular disease progression in diabetes with a unique approach. we attempt to provide a complete perspective of the pathophysiology of vascular complications and then dissect each of the factors that play a key role in accelerating vascular wall alterations in diabetes. each of these factors has been adversely implicated in the initiation and progression of disease to a large extent. in this collection for the first time all these factors would be described under a common canopy. further, the text would emphasize on pathogenesis of micro vascular complications of diabetes, such as retinopathy, neuropathy and nephropathy. pharmacological therapies for treating vascular dysfunction in diabetes mellitus would also be reviewed. this compendium hopefully would be an invaluable replacement to scores of literature on diabetic vascular disease and would be of great interest to clinicians, academicians, medical students and researchers. the book will be divided into seven sections, each emphasizing a common incentive to development of vascular disease in diabetes. section i deals with pathophysiology of diabetic vascular disease, beginning with an update on the global burden of diabetes mellitus and its vascular complications. the pathophysiology and pathogenesis of diabetes associated macrovasculopathy, how hyperglycemia functions as an atherogenic factor, effects of hyperglycemia on smooth muscle accumulation in vascular lesions and genetic susceptibility for increased risk of vascular disease in diabetes will be discussed in the following chapters of this section. the next section (section ii) surveys the process of endothelial dysfunction under hyperglycaemia and hyperinsulinemia and their effects on angiogenesis, vascular remodeling and wound healing. a chapter is also dedicated to the endothelial progenitor cell population and its dysfunction during development of vascular complications in diabetes. section iii will highlight the molecular mechanisms underlying endothelial dysfunction, various pathways such as nitric oxide synthase pathway, oxidative stress pathway, renin – angiotensin system and increased vascular superoxide production in the initiation and progression of vascular disease in diabetes. this section also covers role of endothelin, monocyte derived cytokines, peroxynitrate and adipokines in macrovascular complications of diabetes. metabolic factors such as advanced glycation end products, atherogenic dyslipoproteinaemia, and homocysteine will be reviewed in section iv, whereas an overview of the hemostatic factors such as platelet dysfunction, hyperglycaemia induced thrombin formation and aberrant clot lysis will be dwelled upon in section v.section vi includes chapters on microvascular complications of diabetes which encompasses long term complications of diabetes affecting small blood vessels of the eye, kidneys and nervous system. the pathogenesis and mechanisms of these complications would be detailed here. the final section (section vii) of the book will consider mechanism of action of drugs for treating endothelial dysfunction in diabetes mellitus which would elaborate on lipid regulating therapies such as statins, as well as other therapies such as ace inhibitors, angiotensin ii receptors, insulin, metformin and their effects on enhancing vascular function in diabetes.“/div>divwe intend to invite authors who symbolize a multidisciplinary approach to this complicated disease. the proposed authors include clinicians who understand the trend of vascular complications in their long term clientele, epidemiologists with a holistic view, basic and experimental researchers with years of experience in dissecting the factors leading to endothelial dysfunction and clinical researchers with the skill of translating bench work to the bedside. we expect this book will be of significant value and interest to the same group of clinicians, researchers, post doctoral fellows and medical and non medical graduate students. the novel assimilated insights could stimulate development of mechanism based prevention and therapeutic strategies providing a promising option to limit cardiovascular complications in diabetes mellitus.

Greco-Arab and Islamic Herbal Medicine Traditional System, Ethics, Safety, Efficacy, and Regulatory Issues

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Author by : Bashar Saad
Languange Used : English, France, Spanish, Italia and chinese
Page : 552
Isbn : 9781118002261
Identifier : 1118002261
Release : 2011-04-27
Publisher by : John Wiley & Sons
Category : Science
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Description : Read Now Greco Arab And Islamic Herbal Medicine by Bashar Saad and you can download with pub, pdf, txt, doc, and more file format with free account. this book presents a systematic review on traditional arab herbal medicine including historical background, medical innovations introduced by arab physicians, common roots of arab medicine and western medicine, methodology of drug discovery and therapy in arabic and islamic medicine, a state-of-the-art description of traditional arab herbal medicine, and evidence-based safety and efficacy of arab and islamic medicines. the usage of modern cell biological, biochemical, in vitro and in vivo techniques for the evaluation of medicinal plant safety and efficacy is also discussed. the toxicity of herbal formulations safety, quality assurances, and chemical analytical techniques are introduced in this book.

The Geography, Nature and History of the Tropical Pacific and its Islands

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Author by : Walter M. Goldberg
Languange Used : English, France, Spanish, Italia and chinese
Page : 214
Isbn : 3319695320
Identifier : 9783319695327
Release : 2017-12-08
Publisher by : Springer
Category : Science
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Description : Read Now The Geography Nature And History Of The Tropical Pacific And Its Islands by Walter M. Goldberg and you can download with pub, pdf, txt, doc, and more file format with free account. this volume provides an accessible scientific introduction to the historical geography of tropical pacific islands, assessing the environmental and cultural changes they have undergone and how they are affected currently by these shifts and alterations. the book emphasizes the roles of plants, animals, people, and the environment in shaping the tropical pacific through a cross-disciplinary approach involving history, geography, biology, environmental science, and anthropology. with these diverse scientific perspectives, the eight chapters of the book provide a comprehensive overview of tropical pacific islands from their initial colonization by native peoples to their occupation by colonial powers, and the contemporary changes that have affected the natural history and social fabric of these islands. the tropical pacific islands are introduced by a description of their geological formation, development, and geography. from there, the book details the origins of the island's original peoples and the dawn of the political economy of these islands, including the domestication and trade of plants, animals, and other natural resources. next, readers will learn about the impact of missionaries on pacific islands, and the affects of wold war ii and nuclear testing on natural resources and the health of its people. the final chapter discusses the islands in the context of natural resource extraction, population increases, and global climate change. working together these factors are shown to affect rainfall and limited water resources, as well as the ability to sustain traditional crops, and the capacity of the islands to accomodate its residents.

Reading Human Nature Literary Darwinism in Theory and Practice

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Author by : Joseph Carroll
Languange Used : English, France, Spanish, Italia and chinese
Page : 368
Isbn : 143843524X
Identifier : 9781438435244
Release : 2011-03-01
Publisher by : SUNY Press
Category : Literary Criticism
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Description : Read Now Reading Human Nature by Joseph Carroll and you can download with pub, pdf, txt, doc, and more file format with free account. showcases the latest developments in literary darwinism, a powerful approach that integrates evolutionary social science with literary humanism.

Mixed Effects Models and Extensions in Ecology with R

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Author by : Alain Zuur
Languange Used : English, France, Spanish, Italia and chinese
Page : 574
Isbn : 9780387874586
Identifier : 0387874585
Release : 2009-03-05
Publisher by : Springer Science & Business Media
Category : Science
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Description : Read Now Mixed Effects Models And Extensions In Ecology With R by Alain Zuur and you can download with pub, pdf, txt, doc, and more file format with free account. this book discusses advanced statistical methods that can be used to analyse ecological data. most environmental collected data are measured repeatedly over time, or space and this requires the use of glmm or gamm methods. the book starts by revising regression, additive modelling, gam and glm, and then discusses dealing with spatial or temporal dependencies and nested data.

The Metabolic Ghetto An Evolutionary Perspective on Nutrition, Power Relations and Chronic Disease

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Author by : Jonathan Wells
Languange Used : English, France, Spanish, Italia and chinese
Page : 622
Isbn : 1107009472
Identifier : 9781107009479
Release : 2016-07-21
Publisher by : Cambridge University Press
Category : Business & Economics
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Description : Read Now The Metabolic Ghetto by Jonathan Wells and you can download with pub, pdf, txt, doc, and more file format with free account. a multidisciplinary analysis of the role of nutrition in generating hierarchical societies and cultivating a global epidemic of chronic diseases.

The Evolutionary Biology of Human Body Fatness Thrift and Control

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Author by : Jonathan C. K. Wells
Languange Used : English, France, Spanish, Italia and chinese
Page : 382
Isbn : 0521884209
Identifier : 9780521884204
Release : 2010
Publisher by : Cambridge University Press
Category : Nature
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Description : Read Now The Evolutionary Biology Of Human Body Fatness by Jonathan C. K. Wells and you can download with pub, pdf, txt, doc, and more file format with free account. integrates medical and evolutionary data on the role of body fat in human biology, including the current obesity epidemic.

Plant Physiological Ecology

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Author by : Hans Lambers
Languange Used : English, France, Spanish, Italia and chinese
Page : 540
Isbn : 1475728557
Identifier : 9781475728552
Release : 2013-04-17
Publisher by : Springer Science & Business Media
Category : Science
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Description : Read Now Plant Physiological Ecology by Hans Lambers and you can download with pub, pdf, txt, doc, and more file format with free account. this textbook is remarkable for emphasising that the mechanisms underlying plant physiological ecology can be found at the levels of biochemistry, biophysics, molecular biology and whole-plant physiology. the authors begin with the primary processes of carbon metabolism and transport, plant-water relations, and energy balance. after considering individual leaves and whole plants, these physiological processes are then scaled up to the level of the canopy. subsequent chapters discuss mineral nutrition and the ways in which plants cope with nutrient-deficient or toxic soils. the book then looks at patterns of growth and allocation, life-history traits, and interactions between plants and other organisms. later chapters deal with traits that affect decomposition of plant material and with plant physiological ecology at the level of ecosystems and global environmental processes.

The Cambridge History of Medicine

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Author by : Roy Porter
Languange Used : English, France, Spanish, Italia and chinese
Page : 408
Isbn : 0521864267
Identifier : 9780521864268
Release : 2006-06-05
Publisher by : Cambridge University Press
Category : Medical
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Description : Read Now The Cambridge History Of Medicine by Roy Porter and you can download with pub, pdf, txt, doc, and more file format with free account. the cambridge history of medicine surveys the rise of medicine in the west from classical times to the present. covering both the social and scientific history of medicine, this 2006 volume traces the chronology of key developments and events, engaging with the issues, discoveries, and controversies that have characterized medical progress.

Analyzing meaning An introduction to semantics and pragmatics

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Author by : Paul R. Kroeger
Languange Used : English, France, Spanish, Italia and chinese
Page : 502
Isbn : 3961100349
Identifier : 9783961100347
Release : 2018-02-15
Publisher by : Language Science Press
Category : Language Arts & Disciplines
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Description : Read Now Analyzing Meaning by Paul R. Kroeger and you can download with pub, pdf, txt, doc, and more file format with free account. {this book provides an introduction to the study of meaning in human language, from a linguistic perspective. it covers a fairly broad range of topics, including lexical semantics, compositional semantics, and pragmatics. the chapters are organized into six units: (1) foundational concepts; (2) word meanings; (3) implicature (including indirect speech acts); (4) compositional semantics; (5) modals, conditionals, and causation; (6) tense & aspect. most of the chapters include exercises which can be used for class discussion and/or homework assignments, and each chapter contains references for additional reading on the topics covered. as the title indicates, this book is truly an introduction: it provides a solid foundation which will prepare students to take more advanced and specialized courses in semantics and/or pragmatics. it is also intended as a reference for fieldworkers doing primary research on under-documented languages, to help them write grammatical descriptions that deal carefully and clearly with semantic issues. the approach adopted here is largely descriptive and non-formal (or, in some places, semi-formal), although some basic logical notation is introduced. the book is written at level which should be appropriate for advanced undergraduate or beginning graduate students. it presupposes some previous coursework in linguistics, but does not presuppose any background in formal logic or set theory.