Molecular Pathology The Molecular Basis Of Human Disease

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Molecular Pathology The Molecular Basis of Human Disease

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Author by : William B. Coleman
Languange Used : English, France, Spanish, Italia and chinese
Page : 664
Isbn : 9780123859129
Identifier : 0123859123
Release : 2009-03-10
Publisher by : Academic Press
Category : Science
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Description : Read Now Molecular Pathology by William B. Coleman and you can download with pub, pdf, txt, doc, and more file format with free account. molecular pathology: the molecular basis of human disease provides a current and comprehensive view of the molecular basis and mechanisms of human disease. combining accepted principles with broader theoretical concepts and with contributions from a group of experts, the book looks into disease processes in the context of traditional pathology and their implications for translational molecular medicine. it also discusses concepts in molecular biology and genetics, recent scientific and technological advances in modern pathology, the concept of ""molecular pathogenesis"" of disease, and how disease evolves from normal cells and tissues due to perturbations in molecular pathways. the book describes the integration of molecular and cellular pathogenesis using a bioinformatics approach and a systems biology approach to disease pathogenesis. it also discusses current and future strategies in molecular diagnosis of human disease, and the impact of molecular diagnosis on treatment decisions and the practice of personalized medicine. this book is a valuable resource for students, biomedical researchers, practicing physician-scientists who undertake disease-related basic science and translational research, and pathology residents and other postdoctoral fellows. * exam master® web site will host "self-assessment" questions that students can use to study for the molecular section of the board exam * companion web site – will host a complete set of powerpoint slides: to include images from the book and additional images for teaching; course materials; lecture materials * teaches from the perspective of “integrative systems biology, which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease * outlines the principles and practice of molecular pathology * explains the practice of “molecular medicine and the translational aspects of molecular pathology

Essential Concepts in Molecular Pathology

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Author by : William B. Coleman
Languange Used : English, France, Spanish, Italia and chinese
Page : 462
Isbn : 9780080922188
Identifier : 008092218X
Release : 2010-02-16
Publisher by : Academic Press
Category : Science
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Description : Read Now Essential Concepts In Molecular Pathology by William B. Coleman and you can download with pub, pdf, txt, doc, and more file format with free account. this streamlined "essential" version of the molecular pathology (2009) textbook extracts key information, illustrations and photographs from the main textbook in the same number and organization of chapters. it is aimed at teaching students in courses where the full textbook is not needed, but the concepts included are desirable (such as graduate students in allied health programs or undergraduates). it is also aimed at students who are enrolled in courses that primarily use a traditional pathology textbook, but need the complementary concepts of molecular pathology (such as medical students). further, the textbook will be valuable for pathology residents and other postdoctoral fellows who desire to advance their understanding of molecular mechanisms of disease beyond what they learned in medical/graduate school. offers an essential introduction to molecular genetics and the "molecular" aspects of human disease teaches from the perspective of "integrative systems biology," which encompasses the intersection of all molecular aspects of biology, as applied to understanding human disease in-depth presentation of the principles and practice of molecular pathology: molecular pathogenesis, molecular mechanisms of disease, and how the molecular pathogenesis of disease parallels the evolution of the disease using histopathology. "traditional" pathology section provides state-of-the-art information on the major forms of disease, their pathologies, and the molecular mechanisms that drive these diseases. explains the practice of "molecular medicine" and the translational aspects of molecular pathology: molecular diagnostics, molecular assessment, and personalized medicine each chapter ends with key summary points and suggested readings

Pathobiology of Human Disease A Dynamic Encyclopedia of Disease Mechanisms

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Author by : no defined
Languange Used : English, France, Spanish, Italia and chinese
Page : 5000
Isbn : 0123864577
Identifier : 9780123864574
Release : 2014-08-01
Publisher by : Elsevier
Category : Medical
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Description : Read Now Pathobiology Of Human Disease by no defined and you can download with pub, pdf, txt, doc, and more file format with free account. pathobiology of human disease bridges traditional morphologic and clinical pathology, molecular pathology, and the underlying basic science fields of cell biology, genetics, and molecular biology, which have opened up a new era of research in pathology and underlie the molecular basis of human disease. the work spans more than 48 different biological and medical fields, in five basic sections: human organ systems molecular pathology/basic mechanisms of diseases animal models/other model systems experimental pathology clinical pathology each article provides a comprehensive overview of the selected topic to inform a broad spectrum of readers from research professionals to advanced undergraduate students. reviews quantitative advances in the imaging and molecular analysis of human tissue, new microarray technologies for analysis of genetic and chromosomal alterations in normal and diseased cells and tissues, and new transgenic models of human disease using conditional, tissue-specific gene targeting articles link through to relevant virtual microscopy slides, illustrating side-by-side presentation of "normal" and "disease" anatomy and histology images fully-annotated with many supplementary full color images, graphs, tables, and video files linked to data sets and to live references, enabling researchers to delve deeper and visualize solutions

Principles of Molecular Pathology

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Author by : Anthony Killeen
Languange Used : English, France, Spanish, Italia and chinese
Page : 333
Isbn : 159259431X
Identifier : 9781592594313
Release : 2003-11-07
Publisher by : Springer Science & Business Media
Category : Medical
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Description : Read Now Principles Of Molecular Pathology by Anthony Killeen and you can download with pub, pdf, txt, doc, and more file format with free account. anthony killeen, md, phd, offers a comprehensive yet concise introduction to molecular pathology that encompasses both applied and theoretical knowledge. writing in a very readable style, the author reviews the basic concepts of human molecular biology, explains the principles of the most commonly used analytical methods, and discusses the molecular principles that underlie both inherited diseases and acquired genetic abnormalities that lead to cancer. using common viral infections as examples, the book applies these molecular methods to the detection of microbial pathogens. the growing importance of pharmacogenetics and identity testing in the clinical laboratory is also highlighted.

Molecular Pathology and the Dynamics of Disease

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Author by : Maika G. Mitchell
Languange Used : English, France, Spanish, Italia and chinese
Page : 178
Isbn : 0128146117
Identifier : 9780128146118
Release : 2018-04-16
Publisher by : Academic Press
Category : Law
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Description : Read Now Molecular Pathology And The Dynamics Of Disease by Maika G. Mitchell and you can download with pub, pdf, txt, doc, and more file format with free account. molecular pathology and the dynamics of disease bridges the basic science of, and primary clinical literature on, human disease. topics covered include several major disease areas, such as inflammation and host response, vascular disease, obesity, weight regulation and appetite, cancer biology, drug development, and gene- and cell-based therapeutics that are all presented in a way that emphasizes the interplay between clinical care and investigation. as new technologies and techniques are constantly changing and laboratory scientists plays a critical role in validating data used by clinicians in diagnosing patients, this book provides a timely guide that includes a clinical, research and theory perspective. assimilates theoretical knowledge with practical lab work provides a needed clinical perspective, along with research and theory highlights the impact of basic science on the practice of medicine

Molecular Pathology in Clinical Practice

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Author by : Debra G.B. Leonard
Languange Used : English, France, Spanish, Italia and chinese
Page : 600
Isbn : 0387332278
Identifier : 9780387332277
Release : 2007-11-25
Publisher by : Springer Science & Business Media
Category : Medical
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Description : Read Now Molecular Pathology In Clinical Practice by Debra G.B. Leonard and you can download with pub, pdf, txt, doc, and more file format with free account. this authoritative textbook embodies the current standard in molecular testing for practicing pathologists, and residents and fellows in training. the text is organized into eight sections: genetics, inherited cancers, infectious disease, neoplastic hematopathology, solid tumors, hla typing, identity testing, and laboratory management. discussion of each diagnostic test includes its clinical significance, available assays, quality control and lab issues, interpretation, and reasons for testing. coverage extends to hiv, hepatitis, developmental disorders, bioterrorism, warfare organisms, lymphomas, breast cancer and melanoma, forensics, parentage, and much more. includes 189 illustrations, 45 in full-color. this textbook is a classic in the making and a must-have reference.

Diagnostic Molecular Pathology A Guide to Applied Molecular Testing

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Author by : William B. Coleman
Languange Used : English, France, Spanish, Italia and chinese
Page : 582
Isbn : 0128011572
Identifier : 9780128011577
Release : 2016-10-05
Publisher by : Academic Press
Category : Science
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Description : Read Now Diagnostic Molecular Pathology by William B. Coleman and you can download with pub, pdf, txt, doc, and more file format with free account. diagnostic molecular pathology: a guide to applied molecular testing is organized around disease types (genetic disease, infectious disease, neoplastic disease, among others). in each section, the authors provide background on disease mechanisms and describe how laboratory testing is built on knowledge of these mechanisms. sections are dedicated to general methodologies employed in testing (to convey the concepts reflected in the methods), and specific description of how these methods can be applied and are applied to specific diseases are described. the book does not present molecular methods in isolation, but considers how other evidence (symptoms, radiology or other imaging, or other clinical tests) is used to guide the selection of molecular tests or how these other data are used in conjunction with molecular tests to make diagnoses (or otherwise contribute to clinical workup). in addition, final chapters look to the future (new technologies, new approaches) of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests. diagnostic molecular pathology: a guide to applied molecular testing contains exercises to test readers on their understanding of how molecular diagnostic tests are utilized and the value of the information that can be obtained in the context of the patient workup. readers are directed to an ancillary website that contains supplementary materials in the form of exercises where decision trees can be employed to simulate actual clinical decisions. focuses on the menu of molecular diagnostic tests available in modern molecular pathology or clinical laboratories that can be applied to disease detection, diagnosis, and classification in the clinical workup of a patient explains how molecular tests are utilized to guide the treatment of patients in personalized medicine (guided therapies) and for prognostication of disease features an ancillary website with self-testing exercises where decision trees can be employed to simulate actual clinical decisions highlights new technologies and approaches of applied molecular pathology and how discovery-based research will yield new and useful biomarkers and tests

Cellular and Molecular Pathobiology of Cardiovascular Disease

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Author by : Monte Willis
Languange Used : English, France, Spanish, Italia and chinese
Page : 338
Isbn : 0124055257
Identifier : 9780124055254
Release : 2013-12-23
Publisher by : Academic Press
Category : Science
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Description : Read Now Cellular And Molecular Pathobiology Of Cardiovascular Disease by Monte Willis and you can download with pub, pdf, txt, doc, and more file format with free account. cellular and molecular pathobiology of cardiovascular disease focuses on the pathophysiology of common cardiovascular disease in the context of its underlying mechanisms and molecular biology. this book has been developed from the editors' experiences teaching an advanced cardiovascular pathology course for phd trainees in the biomedical sciences, and trainees in cardiology, pathology, public health, and veterinary medicine. no other single text-reference combines clinical cardiology and cardiovascular pathology with enough molecular content for graduate students in both biomedical research and clinical departments. the text is complemented and supported by a rich variety of photomicrographs, diagrams of molecular relationships, and tables. it is uniquely useful to a wide audience of graduate students and post-doctoral fellows in areas from pathology to physiology, genetics, pharmacology, and more, as well as medical residents in pathology, laboratory medicine, internal medicine, cardiovascular surgery, and cardiology. explains how to identify cardiovascular pathologies and compare with normal physiology to aid research gives concise explanations of key issues and background reading suggestions covers molecular bases of diseases for better understanding of molecular events that precede or accompany the development of pathology

Basic Concepts of Molecular Pathology

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Author by : Philip T. Cagle
Languange Used : English, France, Spanish, Italia and chinese
Page : 190
Isbn : 9780387896267
Identifier : 0387896260
Release : 2009-06-10
Publisher by : Springer Science & Business Media
Category : Medical
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Description : Read Now Basic Concepts Of Molecular Pathology by Philip T. Cagle and you can download with pub, pdf, txt, doc, and more file format with free account. over the past two decades there has been an explosion in knowledge about the molecular pathology of human diseases which accelerated with the sequencing of the human genome in 2003. molecular diagnostics and molecular targeted therapy have contributed to the current concept of personalized patient care that is now routine in many medical centers. as a result, general and subspecialty pathologists, clinical practitioners of all types and radiologists must now have an understanding of the basic concepts of molecular pathology and their role in new diagnostic and therapeutic applications to patient care. the molecular pathology library series was created to bridge the gap between traditional basic science textbooks in molecular biology and traditional medical textbooks for organ-specific diseases. basic concepts of molecular pathology is designed as a stand-alone book to provide the pathologist, clinician or radiologist with a concise review of the essential terminology, concepts and tools of molecular biology that are applied to the understanding, diagnosis and treatment of human diseases in the age of personalized medicine. those medical practitioners, residents, fellows and students who need to refer to the terminology and concepts of molecular pathology in their patient care will find the basic concepts of molecular pathology to be a succinct, portable, user-friendly aid in their practice and studies. the service-based physician will find this handy reference to be valuable at the laboratory benchside, at the patient bedside, at multidisciplinary patient care conferences or as a review for examinations.

Clinical Molecular Medicine Principles and Practice

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Author by : Dhavendra Kumar
Languange Used : English, France, Spanish, Italia and chinese
Page : 704
Isbn : 9780128093566
Identifier : 0128093560
Release : 2019-10-15
Publisher by : Academic Press
Category : Science
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Description : Read Now Clinical Molecular Medicine by Dhavendra Kumar and you can download with pub, pdf, txt, doc, and more file format with free account. clinical molecular medicine: principles and practice presents the latest scientific advances in molecular and cellular biology, including the development of new and effective drug and biological therapies and diagnostic methods. the book provides medical and biomedical students and researchers with a clear and clinically relevant understanding on the molecular basis of human disease. with an increased focus on new practice concepts, such as stratified, personalized and precision medicine, this book is a valuable and much-needed resource that unites the core principles of molecular biology with the latest and most promising genomic advances. illustrates the fundamental principles and therapeutic applications of molecular and cellular biology offers a clinically focused account of molecular heterogeneity includes comprehensive coverage of many different disorders, including growth and development, cardiovascular, metabolic, skin, blood, digestive, inflammatory, neuropsychiatric disorders, and many more

The Molecular Basis of Human Cancer

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Author by : William B. Coleman
Languange Used : English, France, Spanish, Italia and chinese
Page : 873
Isbn : 1597454583
Identifier : 9781597454582
Release : 2016-11-11
Publisher by : Humana Press
Category : Medical
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Description : Read Now The Molecular Basis Of Human Cancer by William B. Coleman and you can download with pub, pdf, txt, doc, and more file format with free account. this book covers the concepts of molecular medicine and personalized medicine. subsequent chapters cover the topics of genomics, transcriptomics, epigenomics, and proteomics, as the tools of molecular pathology and foundations of molecular medicine. these chapters are followed by a series of chapters that provide overviews of molecular medicine as applied broadly to neoplastic, genetic, and infectious diseases, as well as a chapter on molecular diagnostics. the volume concludes with a chapter that delves into the promise of molecular medicine in the personalized treatment of patients with complex diseases, along with a discussion of the challenges and obstacles to personalized patient care. the molecular basis of human cancer, second edition, is a valuable resource for oncologists, researchers, and all medical professionals who work with cancer.

The Molecular Pathology of Autoimmune Diseases

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Author by : Argyrios N Theofilopoulos
Languange Used : English, France, Spanish, Italia and chinese
Page : 1200
Isbn : 9789057026454
Identifier : 9057026457
Release : 2002-12-06
Publisher by : CRC Press
Category : Science
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Description : Read Now The Molecular Pathology Of Autoimmune Diseases by Argyrios N Theofilopoulos and you can download with pub, pdf, txt, doc, and more file format with free account. remarkable advances have been made in the pathogenesis of autoimmunity, such as with bone marrow transplantation, which is becoming a powerful strategy in treating certain life-threatening diseases. the molecular pathology of autoimmune diseases is a concise and centralized resource for information on the topic, with a special focus on the molecular and genetic basis of these disorders. dozens of international experts devote themselves to illuminating the reader in this volume, with discussions on the basic aspects of autoimmune processes to systemic and organ-specific diseases. this volume is an invaluable reference to students and professionals in immunology and related fields.